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Messagepar gsnoopy520 » 18 Mai 2018, 02:44

WASHINGTON cheap nike air vapormax 2018 , July 5 (Xinhua) -- Researchers in Japan have developed a method capable of imaging how cancer cells spread through the body of a mouse, according to a new study published Wednesday.

The new method involved using chemical techniques to make whole mouse bodies and organs highly transparent, thus allowing cancer cells to be viewed multiplying within organs, including the lungs cheap nike air vapormax , intestines, and liver, and traveling through the body to and from new tumors in distant locales.

The study, published in the U.S. journal Cell Reports and led by Hiroki Ueda and Kohei Miyazono of the University of Tokyo cheap nike air max 2018 mens , achieved single-cell resolution for cancer models that grow and metastasize in different ways.

The resulting images reveal cancerous colonies in enough detail to calculate their shapes, volumes, and distributions -- characteristics critical to distinguishing between patterns of metastasis, the research team said.

For example cheap air max 2018 mens , the researchers used the platform to generate a whole-mouse scan of pancreatic cells spreading into the liver and throughout the abdomen.

Another set of images showed a healthy pair of lungs being gradually colonized by cancer cells over the course of two weeks, while a third probed relationships between cancer cells and blood vessels inside the brain.

"Picturing individual cancer cells during metastasis is challenging because they can be scattered all over an entire body," the team said.

"Locating the cancer cells relies on picking up signals from fluorescent proteins that they express, signals that must be preserved when applying tissue clearing methods in pursuit of higher resolution."

Given this difficulty , the researchers took a chemical mixture called Clear Unobstructed BrainBody Imaging Cocktail (CUBIC) that they had previously developed for whole-body imaging preparation and optimized its composition for detecting and viewing cancer cells.

Upon using the modified mixture to turn tissues and vital organs clear, the researchers were able to pluck out fluorescence signals and locate cancer cells in places such as the liver, pancreas, and intestines.

According to the researchers cheap air max 2018 shoes , the new method is already providing a clearer view of certain mysterious steps of metastasis.

In particular, in order to reach a new site within the body and metastasize, a cancer cell must surf the bloodstream, entering and exiting through blood vessel walls.

"Most cancer cells are not so lucky and die during the trip cheap nike air max 2018 ," said Miyazono. "But images obtained through the new method suggest that cells treated with TGF-beta, a protein that regulates cellular growth and differentiation in humans and is produced in increased quantities by some cancers, are far more likely to survive the journey and form malignant outposts."

With preliminary investigations already underway, the researchers believed that cancer imaging and analysis using the CUBIC method "may contribute to addressing currently incurable metastatic diseases."

Xi says China supports EU to be "united cheap air max 2018 , stable, prosperous, open"

Xi arrives in Berlin for state visit to Germany

China, Russia pledge to play role of ballast stone for world peace

Flooded area in C China's Hunan

Weekly choices of Xinhua photo

In pics: sea of vervain in terraced fields in E China

Fireworks show held to mark HK's 20th return anniversary

Water level of Ganjiang River rises due to lasting rainstorm

LONDON Cheap Nike Air Max 90 Pinnacle Black Navy , Jan. 24 (Xinhua) -- Following is the English FA Cup result on Saturday:

Fourth round

Blackburn 3 (Taylor 23, Gestede 78, Conway 89) Swansea 1 (Sigurdsson 21)

Played on Friday

Cambridge United 0 Manchester United 0

CANBERRA, Nov. 19 (Xinhua) -- A third tourist in a week has died while exploring Australia's iconic Great Barrier Reef.

The 60-year old English man could not be revived after fellow divers found him unconscious on the sea floor.

The man was on his second dive of the day from the boat Silver Sonic off the coast of Port Douglas, a popular tourist destination, 1700 km north of Queensland's capital of Brisbane.

Col McKenzie, executive director of the Association of Marine Park Tourism, said that those on board the boat and emergency services did everything in their power to save the man's life.

"They brought him back to the surface, got him on board the boat where they administered the oxygen and used a defibrillator," McKenzie told the Australian Broadcasting Corporation (ABC) on Saturday.

"They called it in to emergency services, a doctor was flown out to the Agincourt helicopter pad, and the doctor took part in that resuscitation event, but again, unsuccessful."

McKenzie said that the Silver Sonic had operated for 11 years and taken 230,000 divers to the coral reef without any fatalities.

"Accidents like this are a tragedy for the surviving family members, the crew and the passengers," he said.

On Wednesday two French tourists in their mid-70s suffered heart attacks and died while snorkeling on the reef at Michaelmas Cay, 55 km southeast off the coast of Port Douglas.

A cardiologist said that the French tourists were likely stung by Irukandji jellyfish, a jellyfish the size of a fingernail that is one of the most venomous creatures in the world.

Daniel Gschwind, CEO of the Queensland Tourism Industry Council, said the sequence of events was incredibly tragic.

"But we have to bear in mind every year 2 million people visit the Great Barrier Reef with commercial operators -- that's a great big number," Gschwind told the ABC.

"Many of them or increasingly... are elderly, and as a generation are far more adventurous, so they end up in situations that carry a slightly increased risk from perhaps the normal circumstances in which they live.

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